mkt.databases.pfam.find_pfam_domain

mkt.databases.pfam.find_pfam_domain(input_id: str, input_position: int, df_ref: DataFrame, col_ref_id: str, col_ref_start: str | None = None, col_ref_end: str | None = None, col_ref_domain: str | None = None) → str | None[source]

Find Pfam domain for a given HGNC symbol and position

Parameters:

  • input_id (str) – Input ID that matches

  • input_position (int) – Codon position in UniProt canonical sequence

  • df_ref (pd.DataFrame) – DataFrame with Pfam domain information

  • col_ref_id (str) – Column that contains the IDs to match to in the df_ref dataframe

  • col_ref_start (None | str) – Column containing the domain start position; if None defaults to “start” (Pfam API default)

  • col_ref_end (None | str) – Column containing the domain end position; if None defaults to “end” (Pfam API default)

  • col_ref_domain (None | str) – Column containing the domain name; if None defaults to “name” (Pfam API default)

Returns:

Pfam domain if found, None if not found

Return type:

str | None