mkt.databases.open_targets.OpenTargetsDrugMoA

class mkt.databases.open_targets.OpenTargetsDrugMoA(url: str = 'https://api.platform.opentargets.org/api/v4/graphql', query_string: str = '\nquery MechanismsOfActionSectionQuery($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n mechanismsOfAction {\n rows {\n mechanismOfAction\n targetName\n targets {\n id\n approvedSymbol\n }\n references {\n source\n urls\n }\n }\n uniqueActionTypes\n uniqueTargetTypes\n }\n parentMolecule {\n id\n name\n }\n childMolecules {\n id\n name\n }\n }\n}\n', variables: dict = <factory>, response: dict | None = None, *, chembl_id: str)[source]

Bases: OpenTargets

Open Targets Drug MoA API client.

__init__(url: str = 'https://api.platform.opentargets.org/api/v4/graphql', query_string: str = '\nquery MechanismsOfActionSectionQuery($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n mechanismsOfAction {\n rows {\n mechanismOfAction\n targetName\n targets {\n id\n approvedSymbol\n }\n references {\n source\n urls\n }\n }\n uniqueActionTypes\n uniqueTargetTypes\n }\n parentMolecule {\n id\n name\n }\n childMolecules {\n id\n name\n }\n }\n}\n', variables: dict = <factory>, response: dict | None = None, *, chembl_id: str) → None

Methods

`__eq__`(other)	Return self==value.
`__init__`([url, query_string, variables, ...])
`__post_init__`()	Initialize the Open Targets Drug MoA API client.
`_stamp_from_response`(res)	Record query datetime + cache provenance from a requests-cache response.
`_stamp_now`()	Record current UTC datetime; cache provenance unknown.
`check_response`(res)	Check the response status code for errors.
`get_moa`()	Get the mechanism of action information for the drug.
`query_api`()	Query a GraphQL API and return result.

Attributes

`__dataclass_fields__`
`__dataclass_params__`
`__match_args__`
`from_cache`	Whether the most recent response was served from requests-cache.
`query_datetime`	UTC datetime the underlying network query was made (cache creation time if served from cache).
`query_string`	GraphQL query string to retrieve drug mechanism of action information.
`response`	Response from the GraphQL API query, if any.
`url`	Base URL for the Open Targets GraphQL API.
`chembl_id`	ChEMBL ID of the drug to query for mechanism of action information.
`variables`	Variables for the GraphQL query retrieve drug mechanism of action information.

__init__(url: str = 'https://api.platform.opentargets.org/api/v4/graphql', query_string: str = '\nquery MechanismsOfActionSectionQuery($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n mechanismsOfAction {\n rows {\n mechanismOfAction\n targetName\n targets {\n id\n approvedSymbol\n }\n references {\n source\n urls\n }\n }\n uniqueActionTypes\n uniqueTargetTypes\n }\n parentMolecule {\n id\n name\n }\n childMolecules {\n id\n name\n }\n }\n}\n', variables: dict = <factory>, response: dict | None = None, *, chembl_id: str) → None

chembl_id: str: ChEMBL ID of the drug to query for mechanism of action information.

get_moa() → dict | None[source]: Get the mechanism of action information for the drug.

query_string: str = '\nquery MechanismsOfActionSectionQuery($chemblId: String!) {\n drug(chemblId: $chemblId) {\n id\n mechanismsOfAction {\n rows {\n mechanismOfAction\n targetName\n targets {\n id\n approvedSymbol\n }\n references {\n source\n urls\n }\n }\n uniqueActionTypes\n uniqueTargetTypes\n }\n parentMolecule {\n id\n name\n }\n childMolecules {\n id\n name\n }\n }\n}\n': GraphQL query string to retrieve drug mechanism of action information.

variables: dict: Variables for the GraphQL query retrieve drug mechanism of action information.